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SMER28-CAS 307538-42-7-Calbiochem

品牌
Sigma-Aldrich
CAS
307538-42-7
货号
573121
规格纯度
A cell-permeable quinazoline compound that augments the cytostatic effects of Rapamycin and acts as an autophagy stimulator both in mammalian cultures in vitro and in a Drosophila melanogaster HD model in vivo.
参考价格
2732.28 *本价格含增值税费
促销
服务
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  • 包邮
  • 增值税票
数量
-+
产品名称:
307538-42-7
SMER28-CAS 307538-42-7-Calbiochem
(6-Bromo-4-allylamino)quinazoline, Small-Molecule Enhancer of Rapamycin-28, Autophagy Inducer II
(6-Bromo-4-allylamino)quinazoline, Small- Molecule Enhancer of Rapamycin-28, Autophagy Inducer II
产品介绍:

产品说明

一般描述

A cell-permeable quinazoline compound that augments the cytostatic effects of Rapamycin (Cat. Nos. 553210 and 553211) in Saccharomyces cerevisiae and acts as an autophagy stimulator both in mammalian cultures in vitro and in a Drosophila melanogaster HD model in vivo. Although SMER28 and Rapamycin do exhibit additive effects on the clearance of cellular autophagy substrates, SMER28 functions independently of Rapamycin by presumably acting on celluar target(s) downstream of the Rapamycin/FKBP12 target, mTOR.
A cell-permeable quinazoline compound that augments the cytostatic effects of Rapamycin (Cat. Nos. 553210 and 553211) in Saccharomyces cerevisiae and acts as an autophagy stimulator both in mammalian cultures in vitro and in a Drosophila melanogaster HD model in vivo. Although SMER28 and Rapamycin do exhibit additive effects on the clearance of cellular autophagy substrates, SMER28 functions independently of Rapamycin by presumably acting on celluar target(s) downstream of the Rapamycin/FKBP12 target, mTOR.

包装

10 mg in Plastic ampoule
Packaged under inert gas

警告

Toxicity: Standard Handling (A)

其他说明

Tian, Y., et al. 2011. FASEB J.25, 1934.Sarkar, S., et al. 2007. Nat. Chem. Biol.3, 331.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式C11H10BrN3
分子量264.12
MDL编号MFCD02166825

产品性质

质量水平100
测定≥95% (HPLC)
形式solid
manufacturer/tradenameCalbiochem®
储存条件OK to freeze
protect from light
颜色pale yellow
溶解性ethanol: 10 mg/mL
DMSO: 100 mg/mL
运输ambient
储存温度2-8℃

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3

Sigma-Aldrich

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