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Swinholide A, Theonella swinhoei-Calbiochem

品牌
Sigma-Aldrich
货号
574776
规格纯度
A dimeric dilactone macrolide that is cytotoxic to a variety of cancer cell lines in vitro.
参考价格
2544.41 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Swinholide A, Theonella swinhoei-Calbiochem
产品介绍:

产品说明

一般描述

A dimeric dilactone macrolide that is cytotoxic to a variety of cancer cell lines in vitro. Disrupts the actin cytoskeleton by sequestering actin dimers with a binding stoichiometry of 1:1, and rapidly severing F-actin. Also possesses antifungal properties.
A dimeric dilactone macrolide isolated from the marine sponge Theonella swinhoei. Cytotoxic to a variety of cancer cell lines in vitro. Disrupts the actin cytoskeleton by sequestering actin dimers with a binding stoichiometry of 1:1, and rapidly severing F-actin. Also possesses antifungal activity.

包装

10 μg in Plastic ampoule
Packaged under inert gas

生化/生理作用

Product does not compete with ATP.
Reversible: no
Cell permeable: no
Primary Target
Disrupts the actin cytoskeleton

警告

Toxicity: Standard Handling (A)

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

其他说明

Saito, S.Y., et al. 1998. J. Biochem. (Tokyo) 123, 571.
Bubb, M.R., et al. 1995. J. Biol. Chem. 270, 3463.
Kobayashi, M., et al. 1994. Chem. Pharm. Bull. 42, 19.
Doi, M., et al. 1991. J. Org. Chem. 56, 3629.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式C78H132O20
分子量1389.87

产品性质

质量水平100
测定≥98% (HPLC)
形式oil
manufacturer/tradenameCalbiochem®
储存条件OK to freeze
protect from light
颜色 colorless
溶解性acetone: soluble
ethanol: soluble
运输ambient
储存温度−20℃

安全信息

危险声明H413
预防措施声明P273 - P501
危险分类Aquatic Chronic 4
储存分类代码10 - Combustible liquids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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