产品说明
应用
Amine functionalized trans-cyclooctene derivative for incorporation of the cyclooctene moiety into carboxyl containing compounds or biomolecules via standard coupling techniques (DCC; EDC etc...). Trans-cyclooctenes are useful in strain-promoted copper-free click chemistry cycloaddition reactions with 1; 2; 4; 5-tetrazines. This cyclooctene will react with tetrazine functionalized compounds or biomolecules without the need for a catalyst to result in a stable covalent linkage. The 4+2 inverse electron demand Diels-Alder cycloaddition between trans-cyclooctene and tetrazines is the fastest biologically compatible ligation technology reported and has had many applications in biological labeling and imaging.
包装
10, 50 mg in clear glass bottle
基本信息
| 经验(实验)分子式 | C12H22N2O2 · HCl |
| 分子量 | 262.78 |
| PubChem化学物质编号 | 329768216 |
| NACRES | NA.22 |
产品性质
| reaction suitability | reaction type: click chemistry |
| 质量水平 | 100 |
| 储存温度 | −20℃ |
| SMILES string | O=C(NCCCN)OC1CCC/C=C/CC1.[H]Cl |
| InChI | 1S/C12H22N2O2.ClH/c13-9-6-10-14-12(15)16-11-7-4-2-1-3-5-8-11;/h1-2,11H,3-10,13H2,(H,14,15);1H/b2-1+; |
| InChI key | GIYQQURLGCGUKK-TYYBGVCCSA-N |
安全信息
| 象形图 | ![]() |
| 警示用语: | Warning |
| 危险声明 | H302 |
| 危险分类 | Acute Tox. 4 Oral |
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |

Sigma-Aldrich
