产品说明
应用
Trovafloxacin mesylate has been used as a test compound in toxicity assay to assess its toxicity in 2D hepatocyte cultures. It has also been used to manipulate the mechanism of apoptotic cell disassembly during apoptosis.
包装
5, 25 mg in glass bottle
生化/生理作用
Trovafloxacin mesylate acts as a pannexin1 (Panx1) inhibitor.
Trovafloxacin mesylate is a broad spectrum antibiotic. Trovafloxacin mesylate blocks the activity of DNA gyrase and topoisomerase IV, enzymes essential in the repliction, transcription, and repair of bacterial DNA.
其他说明
This compound was developed by Pfizer for Immunology research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.
To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
法律信息
Sold for research purposes under agreement from Pfizer Inc.
Pfizer is a registered trademark of Pfizer, Inc.
基本信息
| 经验(实验)分子式 | C20H15F3N4O3 · CH3SO3H |
| 分子量 | 512.46 |
| MDL编号 | MFCD00913361 |
| PubChem化学物质编号 | 329823684 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 100 |
| 测定 | >98% (HPLC) |
| 形式 | powder |
| manufacturer/tradename | Pfizer® |
| 颜色 | white to off-white |
| 溶解性 | DMSO: >10 mg/mL |
| 创始人 | Pfizer |
| 储存温度 | room temp |
| SMILES string | CS(O)(=O)=O.NC1C2CN(CC12)c3nc4N(C=C(C(O)=O)C(=O)c4cc3F)c5ccc(F)cc5F |
| InChI | 1S/C20H15F3N4O3.CH4O3S/c21-8-1-2-15(13(22)3-8)27-7-12(20(29)30)17(28)9-4-14(23)19(25-18(9)27)26-5-10-11(6-26)16(10)24;1-5(2,3)4/h1-4,7,10-11,16H,5-6,24H2,(H,29,30);1H3,(H,2,3,4)/t10-,11+,16+; |
| InChI key | DYNZICQDCVYXFW-AHZSKCOESA-N |
安全信息
| 象形图 |   |
| 警示用语： | Danger |
| 危险声明 | H314 - H361 |
| 预防措施声明 | P201 - P260 - P280 - P301 + P330 + P331 - P303 + P361 + P353 - P305 + P351 + P338 |
| 危险分类 | Repr. 2 - Skin Corr. 1B |
| 储存分类代码 | 8B - Non-combustible, corrosive hazardous materials |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com