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位置:首页 > 品牌 > Sigma-Aldrich > TRPV4 Antagonist I, RN-1734-CAS 946387-07-1-Calbiochem

TRPV4 Antagonist I, RN-1734-CAS 946387-07-1-Calbiochem

品牌
Sigma-Aldrich
CAS
946387-07-1
货号
616520
规格纯度
The TRPV4 Antagonist I, RN-1734, also referenced under CAS 946387-07-1, controls the biological activity of TRPV4. This small molecule/inhibitor is primarily used for Biochemicals applications.
参考价格
1168.11 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
946387-07-1
TRPV4 Antagonist I, RN-1734-CAS 946387-07-1-Calbiochem
2,4-Dichloro-N-isopropyl-N-(2-isopropylaminoethyl)benzenesulfonamide, Transient Receptor Potential Vanilloid-4 Antagonist I, RN1734
RN1734, 2,4-Dichloro-N-isopropyl-N-(2-isopropylaminoethyl)benzenesulfonamide, Transient Receptor Potential Vanilloid-4 Antagonist I
产品介绍:

产品说明

一般描述

A cell-permeable benzenesulfonamide compound that acts as a selective TRPV4 antagonist and inhibits TRPV4 agonist 4α-PDD- (Cat. No. 524394) stimulated Ca2+ influx (IC50 = 2.3, 3.2 and 5.9 µM, respectively, in HEK293 expressing human, rat, or mouse TRPV4) without affecting the activity of three other human TRP (transient receptor potential) channels, including capsaicin- (Cat. No. 211275) activated TRPV1, camphor-activated TRPV3, and methanol-activated TRPM8 (IC50 >30 µM).
A cell-permeable benzenesulfonamide compound that selectively antagonizes TRPV4 agonist 4α-PDD- (Cat. No. 524394) stimulated Ca2+ influx (IC50 = 2.3, 3.2 and 5.9 µM, respectively, in HEK293 expressing human, rat, or mouse TRPV4) without affecting the activity of three other human TRP (transient receptor potential) channels, including capsaicin- (Cat. No. 211275) activated TRPV1, camphor-activated TRPV3, and methanol-activated TRPM8 (IC50 >30 µM).

包装

10 mg in Glass bottle
Packaged under inert gas

警告

Toxicity: Standard Handling (A)

其他说明

Vincent, F., et al. 2009. Biochem. Biophys. Res. Commun.389, 490.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式C14H22Cl2N2O2S
分子量353.31
MDL编号MFCD00129453

产品性质

质量水平100
测定≥95% (HPLC)
形式solid
manufacturer/tradenameCalbiochem®
储存条件OK to freeze
protect from light
颜色 yellow
溶解性DMSO: 50 mg/mL
运输ambient
储存温度2-8℃

安全信息

储存分类代码11 - Combustible Solids
WGKnwg
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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