产品说明
一般描述
The TSKgel SuperSW and UltraSW mAb columns consist of three specialized columns designed for the separation and analysis of monoclonal antibodies (mAb). While mAbs can be analyzed using many different modes of HPLC, size exclusion is best for aggregation, dimer, and fragmentation, making it the best method for heterogeneity studies.TSKgel SuperSW mAb HTP columns provide high throughput analysis of mAb monomer and dimer and is UHPLC compatible. These short, narrow bore (15 cm x 4.6 mm ID) silica-based stainless steel columns offer reduced lot-to-lot variation, long column life, reduction of unspecified adsorption, and superior recovery of aggregates. The TSKgel SW mAb HTP columns utilize a unique pore-controlled technology, which produces a shallow calibration curve in the molecular weight region of a typical monoclonal antibody.
外形
Shipped in 0.05% NaN3 and 0.1 M Na2SO4 in 0.1 M phosphate buffer, pH 6.7.
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法律信息
TSKgel is a registered trademark of Tosoh Corporation
产品性质
| 物料 | stainless steel |
| agency | suitable for USP L20 suitable for USP L59 |
| 产品线 | TSKgel® |
| manufacturer/tradename | Tosoh SuperSW mAb HTP Guard Column, 22858 |
| 参数 | ≤0.5 M salt concentration 0-100% aqueous soluble organic solvents 0.5 mL/min flow rate 10-30 ℃ temperature |
| technique(s) | HPLC: suitable |
| 长度 × 内径 | 2 cm × 3 mm |
| 基质 | silica particle platform |
| 基质活性基团 | diol phase |
| 粒径 | 4 μm |
| 孔径 | 250 Å pore size |
| 操作pH | 2.5 - 7.5 |
| 分离技术 | size exclusion (SEC) |
Sigma-Aldrich
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