V-ATPase Inhibitor, KM91104-Calbiochem

产品说明

一般描述

A cell-permeable, non-macrolide small molecule V-ATPase inhibitor that specifically targets the a3-b2 subunit protein protein interation of V-ATPase (IC₅₀ of 2.3 µM), in vitro. It is also shown to inhibit osteoclast resorption (IC₅₀ of 1.2 µM) on both synthetic hydroxyapatite surfaces and dentin slices in an in vitro osteoclast model, RANKL-differentiated RAW 264.7 cells, without significantly affecting RAW 264.7 cell viability or RANKL-mediated osteoclast differentiation.

包装

10 mg in Glass bottle
Packaged under inert gas

警告

Toxicity: Standard Handling (A)

重悬

Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

其他说明

Kartner, N., et al. 2010. J. Biol. Chem.285, 37476.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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