产品说明
包装
5, 25 mg in glass bottle
生化/生理作用
WAY-208466 is a high affinity (Ki = 4.8 nM) 5-HT6 receptor agonist. In HeLa cells expressing cloned human 5-HT6, the compound induced cAMP production (EC50 = 7.3 nM; Emax = 100%). WAY-208466 increases cortical GABA levels and exhibits anxiolytic activity in rat studies.
其他说明
This compound was developed by Pfizer for Neuroscience research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.
To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
法律信息
Sold for research purposes under agreement from Pfizer Inc.
Pfizer is a registered trademark of Pfizer, Inc.
基本信息
| 经验(实验)分子式 | C17H18FN3O2S · 2HCl |
| 分子量 | 420.33 |
| MDL编号 | MFCD28384460 |
| PubChem化学物质编号 | 329823827 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | powder |
| manufacturer/tradename | Pfizer® |
| 颜色 | white to beige |
| 溶解性 | H2O: 5 mg/mL, clear (warmed) |
| 创始人 | Pfizer |
| 储存温度 | room temp |
| SMILES string | CN(C)CCN1C=C(S(C2=CC=CC(F)=C2)(=O)=O)C3=CC=CN=C31 |
| InChI | 1S/C17H18FN3O2S/c1-20(2)9-10-21-12-16(15-7-4-8-19-17(15)21)24(22,23)14-6-3-5-13(18)11-14/h3-8,11-12H,9-10H2,1-2H3 |
| InChI key | SFSFIDVAEMDPIP-UHFFFAOYSA-N |
安全信息
| 象形图 |  |
| 警示用语： | Warning |
| 危险声明 | H315 - H319 - H335 |
| 预防措施声明 | P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338 |
| 危险分类 | Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
| 靶器官 | Respiratory system |
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
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