产品说明
免疫原
The epitope recognized by PLA0305 maps to a region between residue 873 to 923 of human p30 DBC Protein using the numbering given in entry NP_066997.3 (GeneID 57805).
外形
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
其他说明
The DBC1 (Deleted in Breast Cancer Gene 1 protein) gene is located in a region frequently deleted in breast cancers. In its uncleaved form, DBC1 is localized to the nucleus. Upon cleavage by caspase activity, DBC1 becomes localized to the cytoplasm and functions to promote apoptosis. DBC1 has also been found to bind directly to the estrogen receptor alpha (ERalpha) hormone binding domain to modulate ERalpha expression and mediate hormone-independent breast cancer cell survival.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 质量水平 | 100 |
| 生物来源 | goat |
| 抗体形式 | affinity purified immunoglobulin |
| antibody product type | primary antibodies |
| 等级 | Powered by Bethyl Laboratories, Inc. |
| species reactivity | human, mouse |
| 浓度 | 1 mg/mL |
| technique(s) | immunohistochemistry: 1:2,000-1:5,000 immunoprecipitation (IP): 2- 10 μg/mg western blot: 1:2,000-1:10,000 |
| 登记号 | NP_066997.3 |
| 运输 | wet ice |
| 储存温度 | 2-8℃ |
| Gene Information | human ... CCAR2(57805) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | nwg |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
