产品说明
免疫原
Full-length human Cdc34 expressed in E. coli.
应用
Optimal dilutions/concentrations should be determined by the researcher.
生化/生理作用
Cdc34 is a ubiquitin conjugating enzyme (UBC) or E2 that has been shown to be essential for the G1 to S phase transition in S. cerevisiae. Human Cdc34 fully complements the budding yeast Cdc34 temperature sensitive mutant phenotype. In egg extracts of the frog Xenopus laevis, Cdc34 has been shown to be required for the onset of DNA replication and appears to function in a multi-protein complex. Also, Cdc34 is highly conserved among vertebrates and is likely to function in a similar manner in all eukaryotes to regulate the start of DNA synthesis.
特点和优势
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其他说明
Purification: Protein G affinity purified
外形
Phosphate-buffered saline, pH 7.2, no preservative added.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
产品性质
质量水平 | 100 |
生物来源 | mouse |
偶联物 | unconjugated |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | 14B5, monoclonal |
形式 | buffered aqueous solution |
species reactivity | human |
浓度 | 1mg/mL |
technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable immunoprecipitation (IP): suitable indirect immunofluorescence: suitable western blot: suitable |
同位素/亚型 | IgG1 |
UniProt登记号 | P49427 |
运输 | wet ice |
储存温度 | −20℃ |
Gene Information | human ... CDC34(997) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich