Monoclonal Anti-RAD1 antibody produced in mouse

产品说明

免疫原

Amino terminal fragment of human Rad1 purified from E. coli.

应用

For WB: Use at a dilution of 1:1,000. Detects a band of approximately 28 kDa (predicted molecular weight: 34 kDa). Optimal dilutions/concentrations should be determined by the researcher.

生化/生理作用

Human Rad1 is a component of a heterotrimeric PCNA-like complex that also contains the Rad9 and Hus1 proteins. This complex is believed to be involved in cellular responses to DNA damage, possibly by associating with Rad17 and several components of the PCNA-loading heteropentamer, replication factor C. Human Rad1 exhibits significant homology to Rad1 from S. pombe, and its expression in yeast rad1 mutants has been shown to partially restore radiation resistance and G2-checkpoint activity. It has also been shown to possess exonuclease activity.

特点和优势

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外形

Phosphate-buffered saline, pH 7.2, conatining no preservatives

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

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