Rabbit anti-NPM1 Antibody, Affinity Purified

产品说明

免疫原

The epitope recognized by PLA0254 maps to a region between residue 250 and 294 of human nucleophosmin using the numbering given in entry NP_002511.1 (GeneID 4869).

外形

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

其他说明

Nucleophosmin (NPM1) is involved in diverse cellular processes such as ribosome biogenesis, centrosome duplication, protein chaperoning, histone assembly, cell proliferation, and regulation of tumor suppressors TP53/p53 and ARF. It associates with nucleolar ribonucleoprotein structures and binds single-stranded nucleic acids. NPM1 binds ribosomes presumably to drive ribosome nuclear export. Chromosomal aberrations involving NPM1 have been identified in several types of leukemia [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P06748].

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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