产品说明
免疫原
The epitope recognized by PLA0219 maps to a region between residue 244 and 294 of human survival of motor neuron 1 using the numbering given in entry NP_000335.1 (GeneID 6606).
外形
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
其他说明
Survival motor neuron protein (SMN1) has been identified as the gene that is defective in spinal muscular atrophy (SMA), a neurodegenerative autosomal recessive disease characterized by paralysis and muscular atrophy which results from the loss of motor neurons in the spinal cord. There are two closely related SMN genes that do not appear to be functionally redundant. SMN1 represents the telomeric copy while SMN2 represents the centromeric copy. In the cell, SMN1 is part of a large complex of proteins involved in snRNP biogenesis. The functional role of SMN1 is proposed to play a role in messenger and ribosomal RNA transcription and processing.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 100 |
抗体形式 | affinity purified immunoglobulin |
antibody product type | primary antibodies |
等级 | Powered by Bethyl Laboratories, Inc. |
species reactivity | human |
technique(s) | immunoprecipitation (IP): 2-5 μg/mg western blot: 1:2,000- 1:10,000 |
登记号 | NP_000335.1 |
运输 | wet ice |
储存温度 | 2-8℃ |
Gene Information | rabbit ... SMN1(6606) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | nwg |
Sigma-Aldrich