产品说明
免疫原
Synthetic peptide directed towards the middle region of human ARAF
应用
Anti-ARAF antibody produced in rabbit is suitable for western blotting at a concentration of 1μg/mL.
生化/生理作用
ARAF gene is a proto-oncogene belonging to the RAF subfamily, which encodes cytoplasmic protein serine/threonine kinases. It is localized at human chromosome Xp11.3-p11.23 and is widely expressed in mouse urogenital tissues. It plays a crucial role in cell growth and development. Dimerization of the kinase ARAF facilitates the MAPK activity and cell migration in a cell type-dependent manner. Mutation in ARAF gene causes lung adenocarcinoma associated with sorafenib-sensitive response.
序列
Synthetic peptide located within the following region: PRGSPSPASVSSGRKSPHSKSPAEQRERKSLADDKKKVKNLGYRDSGYYW
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 67 kDa |
| species reactivity | pig, bovine, sheep, mouse, horse, human, rat |
| 浓度 | 0.5 mg - 1 mg/mL |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| NCBI登记号 | NP_001645 |
| UniProt登记号 | P10398 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... ARAF(369) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
