产品说明

一般描述

ALF codes for a germ cell-specific component of the general transcription factor TFIIA subunit. It is involved in stabilizing DNA interactions with TBP. ALF may also be involved in regulating testicular functions.
Rabbit Anti-ALF antibody recognizes human, and bovine ALF.

免疫原

Synthetic peptide directed towards the N terminal region of human ALF

应用

Rabbit Anti-ALF antibody can be used for western blot applications at a concentration of 0.4μg/ml.

生化/生理作用

The assembly and stability of the RNA polymerase II transcription pre-initiation complex on a eukaryotic core promoter involves the effects of TFIIA on the interaction between TATA-binding protein (TBP) and DNA. ALF is a germ cell-specific counterpart of the large (alpha/beta) subunit of general transcription factor TFIIA that is able to stabilize the binding of TBP to DNA and may be uniquely important to testis biology.

序列

Synthetic peptide located within the following region: VIPAGRTLPSFTTAELGTSNSSANFTFPGYPIHVPAGVTLQTVSGHLYKV

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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