Anti-AMN1 antibody produced in rabbit

产品说明

免疫原

Synthetic peptide directed towards the N terminal region of human AMN1

应用

Anti-AMN1 antibody produced in rabbit is suitable for western blotting at a concentration of 1μg/mL.

生化/生理作用

In S.cerevisiae, the daughter cell activates an antagonist of mitotic exit network pathway by induction of Amn1 protein that binds to Tem1, a ras-related GTPase, and prevents its association with its target kinase Cdc15. Thus, AMN1 helps the daughter cell to exit from mitotic exit and reset the cell cycle in G1. Failure of Amn1 function results in defects of both the spindle assembly and nuclear orientation checkpoints and delays turning off Cdc14 in G1.

序列

Synthetic peptide located within the following region: PRPRRVSQLLDLCLWCFMKNISRYLTDIKPLPPNIKDRLIKIMSMQGQIT

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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