ANTI-ASB10(N-TERMINAL) antibody produced in rabbit

产品说明

一般描述

ASB10 belongs to the ankyrin repeat and SOCS box (ASB) family and the suppressor of cytokine signaling (SOCS) box protein superfamily. It consists of a number of ankyrin (ANK) repeat protein domains and a C-terminal suppressor of cytokine signaling (SOCS) box. Depending on the number of ankyrin (ANK) repeat protein domains, ASB family is divided into 1-18 types. ASB10 is composed of seven ANK repeat domains and a SOCS box at the C-terminus end.

应用

ANTI-ASB10(N-TERMINAL) antibody produced in rabbit is suitable for western blot at a dilution of 1:1000.

生化/生理作用

ASB10 (ankyrin repeat and SOCS box containing 10) plays a vital role in the ubiquitination-mediated proteasomal and autophagy-lysosomal degradation pathways. The ANK repeat containing domain is responsible for protein-protein interactions whereas the SOCS (suppressor of cytokine signaling) box motif helps in ubiquitination of the protein by binding to the multisubunit E3 ubiquitin ligase complex. ASB family interacts specifically with Cul5-Rbx2 in cells to form an E3 ubiquitin (Ub) ligase complex.

外形

Supplied in PBS with 0.09% (W/V) sodium azide

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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