Anti-BARHL2 antibody produced in rabbit

产品说明

一般描述

BarH like homeobox 2 (BARHL2) belongs to BARH gene family and is expressed in retinal ganglion cells (RGCs), amacrine cells (ACs), and horizontal cells. In human chromosome, the gene BARHL2 is located on 1p22.2.

免疫原

Synthetic peptide directed towards the middle region of human BARHL2

生化/生理作用

BARHL2 and BARHL1 are two homeobox genes in mouse and human, which are highly related to the Bar Drosophila genes. BARHL2 plays a key role in retinal development, including regulation of amacrine cells and retinal neuron subtype specification, differentiation and survival of retinal ganglion cells. Loss of BARHL2 leads to the development of cholinergic amacrine cells and devoid of glycinergic and GABAergic amacrine cells. Methylation of BARHL2 serves as a marker for predicting early and advanced stage of gastric cancer.

序列

Synthetic peptide located within the following region: REITSSRESPPVRAKKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDL

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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