产品说明
一般描述
The open reading frame C12orf42 is a hypotheical protein of unknown function and is located 22.7kb upstream of 2 SNPs (single nucleotide polymorphisms) associated with restenosis. This gene was seen to be upregulated upon treatment with TGF-β superfamily of growth factors called bone morphogenetic proteins (BMPs) on global gene transcription in breast cancer cell lines. Chromosome 12 makes up about 4.5% of the human genome. It encodes over 1,100 genes within 132 million bases. A number of deformities such as osteoarthritis, kniest dysplasia, hypochondrogenesis and achondrogenesis are linked to chromosome 12. A gene for Noonan syndrome, which includes heart and facial developmental defects is located on chromosome 12.
免疫原
Synthetic peptide directed towards the N terminal region of human C12orf42
应用
Anti-C12ORF42 antibody produced in rabbit is suitable for western blotting at a concentration of 1μg/mL.
生化/生理作用
The exact function of C12orf42 remains unknown.
序列
Synthetic peptide located within the following region: PRCSVSTVSFDEESYEEFRSSPAPSSETDEAPLIFTARGETEERARGAPK
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
产品性质
生物来源 | rabbit |
质量水平 | 100 |
偶联物 | unconjugated |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
形式 | buffered aqueous solution |
分子量 | 40 kDa |
species reactivity | human |
浓度 | 0.5 mg - 1 mg/mL |
technique(s) | western blot: suitable |
NCBI登记号 | NP_001092806 |
UniProt登记号 | Q96LP6 |
运输 | wet ice |
储存温度 | −20℃ |
Gene Information | human ... C12orf42(374470) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich