产品说明
一般描述
CBX1 is a conserved heterochromatin protein that interacts with centromeres. It is involved in modulating chromatin morphology and epigenetics.
Rabbit Anti-CBX1 antibody recognizes canine, chicken, human, mouse, rat, and bovine CBX1.
免疫原
Synthetic peptide directed towards the middle region of human CBX1
应用
Rabbit Anti-CBX1 antibody can be used for western blot applications at a concentration of 1.25 μg/ml.
生化/生理作用
CBX1 is the component of heterochromatin. CBX1 recognizes and binds histone H3 tails methylated at ′Lys-9′, leading to epigenetic repression. CBX1 interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane.Heterochromatin protein-1 (HP1) is localized at heterochromatin sites, where it mediates gene silencing.[supplied by OMIM].
序列
Synthetic peptide located within the following region: PDLIAEFLQSQKTAHETDKSEGGKRKADSDSEDKGEESKPKKKKEESEKP
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 21 kDa |
| species reactivity | dog, rat, horse, mouse, bovine, human, rabbit, pig |
| 浓度 | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| NCBI登记号 | NP_001120700 |
| UniProt登记号 | P83916 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... CBX1(10951) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
