产品说明
一般描述
CCT4 is a subunit of the TCP1 complex that regulates protein folding. Mutations in CCT4 have been associated with hereditary sensory neuropathy in rats. CCT4 mutant yeasts also exhibit functional/structural impairment in budding, cell shape and actin organization.
Rabbit Anti-CCT4 antibody recognizes human, mouse, rat, bovine, zebrafish, and chicken CCT4.
免疫原
Synthetic peptide directed towards the C terminal region of human CCT4
应用
Rabbit Anti-CCT4 antibody is suitable for western blot applications at a concentration of 0.5 μg/ml.
生化/生理作用
The CCT (chaperonin containing TCP-1) complex functions as a molecular chaperone in the eukaryotic cytosol. CCT4 interacts with human cyclin E which has been implicated in positive control of the G1/S phase transition.
序列
Synthetic peptide located within the following region: AFADAMEVIPSTLAENAGLNPISTVTELRNRHAQGEKTAGINVRKGGISN
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 58 kDa |
| species reactivity | human, rat |
| 浓度 | 0.5 mg - 1 mg/mL |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| NCBI登记号 | NP_006421 |
| UniProt登记号 | Q53QP9 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... CCT4(10575) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
