产品说明
免疫原
The immunogen for anti-CDK4 antibody: synthetic peptide derected towards the C terminal of human CDK4
应用
Anti-CDK4 (AB2) antibody produced in rabbit is suitable for western blotting at a concentration of 1 μg/ml.
生化/生理作用
CDK4 forms a complex with cyclin D1 and regulates cell proliferation during the G1 phase. It also binds with human p16 and inhibits the activity of the CDK4/cyclin D complex in cells that lack retinoblastoma protein. CDK4 forms a complex with pRB and E2F1 proteins that modulate the secretion of insulin by pancreatic β-cells.
序列
Synthetic peptide located within the following region: PRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRALQHSYLHKDEGNPE
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| MDL编号 | MFCD00282839 |
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 34 kDa |
| species reactivity | rabbit, canine, rat, human, pig |
| 浓度 | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| NCBI登记号 | NP_000066 |
| UniProt登记号 | P11802 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... CDK4(1019) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
