Anti-CHRNA2 antibody produced in rabbit

产品说明

一般描述

Rabbit polyclonal anti CHRNA2 antibody reacts with human cholinergic receptor, nicotinic, α-2 subunit.
Neuronal nicotinic acetylcholine receptors (nAChR) are homo- or heteropentameric complexes composed of homologous α and β subunits. Nicotinic acetylcholine receptors are broadly expressed in the nervous system where they help regulate processes such as excitability, neurotransmitter release and neuromuscular contraction. The specificity and function of various nAChRs is determined in part by their specific α and β subunits compositions. Neuronal acetylcholine receptor subunit α-2 (CHRNA2) is an important component of the nAChR component family.

免疫原

Synthetic peptide directed towards the N terminal region of human CHRNA2

应用

Rabbit polyclonal anti CHRNA2 antibody is used to tag cholinergic receptor, nicotinic, α-2 for detection and quantitation by immunocytochemical and immunohistochemical (IHC) techniques. It is used as a probe to determine the presence and roles of cholinergic receptor, nicotinic, α-2 in the function and specificity of neuronal nicotinic acetylcholine receptors. Anti- CHRNA2 antibody produced in rabbit is suitable for western blotting at a concentration of 1 μg/ml. For immunohistochemistry of paraffin-embedded tissue sections, a concentration of 4-8 μg/ml is suitable.

序列

Synthetic peptide located within the following region: TKLSLWWLLLTPAGGEEAKRPPPRAPGDPLSSPSPTALPQGGSHTETEDR

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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