产品说明
免疫原
Synthetic peptide directed towards the middle region of human CHRNB3
应用
Anti-CHRNB3 antibody produced in rabbit is suitable for western blotting at a concentration of 0.03 μg/ml.
生化/生理作用
CHRNB3 is a transmembrane oligomeric ligand-gated nicotinic receptor when activated by cholinergic binding induces ion channel opening for the movement of positive ions. Nicotinic acetylcholine receptors mediate presynaptic, postsynaptic and extrasynaptic signaling. High level expression of CHRNB3 has been observed in the substantia nigra, the ventral tegmental area (VTA), the locus coeruleus and the retina. CHRNB3 has been implicated in subjective responses to tobacco and alcohol consumption.
序列
Synthetic peptide located within the following region: YDGTMVDLILINENVDRKDFFDNGEWEILNAKGMKGNRRDGVYSYPFITY
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 53 kDa |
| species reactivity | rabbit, mouse, dog, rat, guinea pig, human, bovine |
| 浓度 | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| NCBI登记号 | NP_000740 |
| UniProt登记号 | Q8BMN3 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... CHRNB3(1142) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
