Anti-CLCNKA antibody produced in rabbit

产品说明

一般描述

CLCNKA is a chloride channel, voltage sensitive protein that may regulate renal reabsorption of salts. It may also regulate potassium recycling in the inner ear. Genetic variations in CLCNKA have been linked to cardiac and hypertensive disorders.
Rabbit Anti-CLCNKA antibody recognizes human CLCNKA.

免疫原

Synthetic peptide directed towards the N terminal region of human CLCNKA

应用

Rabbit Anti-CLCNKA antibody is suitable for western blot applications at a concentration of 1 μg/ml.

生化/生理作用

CLCNKA is a member of the CLC family of voltage-gated chloride channels. It is predicted to have 12 transmembrane domains, and requires a beta subunit called barttin to form a functional channel. It is thought to function in salt reabsorption in the kidney and potassium recycling in the inner ear. This gene is a member of the CLC family of voltage-gated chloride channels. The encoded protein is predicted to have 12 transmembrane domains, and requires a beta subunit called barttin to form a functional channel. It is thought to function in salt reabsorption in the kidney and potassium recycling in the inner ear. The gene is highly similar to CLCNKB, which is located 10 kb downstream from this gene. Multiple transcript variants encoding different isoforms have been found for this gene.

序列

Synthetic peptide located within the following region: MEELVGLREGFSGDPVTLQELWGPCPHIRRAIQGGLEWLKQKVFRLGEDW

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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