Anti-COLEC12 (AB1) antibody produced in rabbit

产品说明

一般描述

COLEC12 is a scavenger receptor that belongs to the C lectin family. This cell-surface glycoprotein has been implicated in host defense. It is also involved in the elimination of oxidatively altered LDLs by vascular endothelial cells. Furthermore, COLEC12 can recognize carbohydrate antigens on microorganisms and aid their removal.
Rabbit Anti-COLEC12 recognizes human, mouse and rat COLEC12.

免疫原

Synthetic peptide directed towards the middle region of human COLEC12

应用

Rabbit Anti-COLEC12 (AB1) antibody can be used for western blotting applications at a concentration of 0.5μg/ml.

生化/生理作用

COLEC12 encodes a member of the C-lectin family, proteins that possess collagen-like sequences and carbohydrate recognition domains. This protein is a scavenger receptor, a cell surface glycoprotein that can bind to carbohydrate antigens on microorganisms facilitating their recognition and removal. In addition, these receptors can recognize oxidized phospholipids so they may also participate in removing oxidatively damaged or apoptotic cells.

序列

Synthetic peptide located within the following region: GLGGDGGGCGGGGSGGGGAPRREPVPFPSGSAGPGPRGPRATESGKRMDC

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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