Anti-DCXR antibody produced in rabbit

产品说明

一般描述

Dicarbonyl/L-xylulose reductase (DCXR, P34H) is an enzyme that converts L-xylulose into xylitol and reduces various α-dicarbonyl compounds. DCXR is involved in the uronate cycle of glucose metabolism. Decreased level of DCXR membranous expression may be associated with malignant progression of melanocytic lesions. P34H, an epididymal sperm protein, may be a predictor of in vitro fertilization outcome.

特异性

Anti-DCXR polyclonal antibody reacts with bovine, pig, chicken, canine, human, mouse, and rat dicarbonyl/L-xylulose reductase proteins.

免疫原

Synthetic peptide directed towards the middle region of human DCXR

应用

Anti-DCXR polyclonal antibody is used to tag dicarbonyl/L-xylulose reductase proteins for detection and quantitation by Western blotting and in cells and tissues by immunohistochemical (IHC) techniques. It is used as a probe to study the role of dicarbonyl/L-xylulose reductase proteins in sperm capacitation, xylulose metabolism and the uronate cycle of glucose metabolism.

生化/生理作用

DCXR is an enzyme that has both diacetyl reductase and L-xylulose reductase activities.DCXR is an enzyme that has both diacetyl reductase (EC 1.1.1.5) and L-xylulose reductase (EC 1.1.1.10) activities (Nakagawa et al., 2002).[supplied by OMIM].

序列

Synthetic peptide located within the following region: STKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSMGQATWSDPHKAKTM

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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