产品说明
一般描述
ELL encodes an elongation factor that can enhance the catalytic function of RNA polymerase II transcription by inhibiting pausing at several sites along the DNA.
Rabbit Anti-ELL (AB1) antibody associates with rat, human, mouse, canine, chicken, bovine, and zebrafish ELL.
免疫原
Synthetic peptide directed towards the C terminal region of human ELL
应用
Rabbit Anti-ELL (AB1) antibody can be used for immunohistochemistry (4-8μg/ml, using paraffin-embedded sections) and western blot (7.5μg/ml) applications.
生化/生理作用
ELL was shown to encode a previously uncharacterized elongation factor that can increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by polymerase at multiple sites along the DNA. Functionally, ELL resembles Elongin (SIII), a transcription elongation factor regulated by the product of the von Hippel-Lindau (VHL) tumor suppressor gene.
序列
Synthetic peptide located within the following region: TQLDAQLRQLSQGSEEYETTRGQILQEYRKIKKTNTNYSQEKHRCEYLHS
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 68 kDa |
| species reactivity | bovine, dog, human, horse |
| 浓度 | 0.5 mg - 1 mg/mL |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| NCBI登记号 | NP_006523 |
| UniProt登记号 | P55199 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... ELL(8178) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
