产品说明
一般描述
ETS2 belongs to the Ets family of transcription factors that are crucial mediators of extracellular matrix remodeling. The Ets family members are regulators of bone and cartilage development.
免疫原
The immunogen for anti-ETS2 antibody: synthetic peptide derected towards the middle region of human ETS2
应用
Anti-ETS2 antibody produced in rabbit is suitable for western blotting at a concentration of 0.25 μg/ml.
生化/生理作用
ETS family members have binding sites for AP-1 and MAPK proteins. ETS2 significantly regulates the skeletal development and differentiation of osteoblasts. Decreased expression of ETS2 results in skeletal abnormalities similar to those observed in humans with Down′s syndrome. Studies show that ETS2 promotes angiogenesis breast cancer progression.
序列
Synthetic peptide located within the following region: FESFEDDCSQSLCLNKPTMSFKDYIQERSDPVEQGKPVIPAAVLAGFTGS
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 53 kDa |
| species reactivity | mouse, human, guinea pig, rat, dog |
| 浓度 | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| NCBI登记号 | NP_005230 |
| UniProt登记号 | P15036 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... ETS2(2114) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
