产品说明
一般描述
EVI1 is a zinc-finger protein that functions as a transcription factor. This protein has been implicated in leukemic transformation of hematopoietic stem cells. Additionally, Evi-1 is known to function as a repressor of TGF-β signaling.
Rabbit Anti-EVI1 (AB2) antibody recognizes human, bovine, rat, canine, mouse, and chicken EVI1.
免疫原
Synthetic peptide directed towards the C terminal region of human EVI1
应用
Rabbit Anti-EVI1 (AB2) antibody is suitable for use in western blot applications at a concentration of 0.5μg/ml.
生化/生理作用
EVI1 promotes cell proliferation by interacting with BRG1 and blocking the repression of BRG1 on E2F1 activity.
序列
Synthetic peptide located within the following region: HFTDSLKMRKMEDNQYSEAELSSFSTSHVPEELKQPLHRKSKSQAYAMML
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 118 kDa |
| species reactivity | horse, bovine, dog, rabbit, rat, human, guinea pig |
| 浓度 | 0.5 mg - 1 mg/mL |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| NCBI登记号 | NP_005232 |
| UniProt登记号 | Q03112 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... EVI1(2122) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
