Anti-FES antibody produced in rabbit

产品说明

免疫原

Synthetic peptide directed towards the N terminal region of human FES

应用

Anti-FES antibody produced in rabbit is suitable for western blotting at a concentration of 1μg/mL.

生化/生理作用

FES is a proto-oncogene that encodes a protein tyrosine kinase, which is the cellular homologue of a feline sarcoma retrovirus protein with transforming capabilities. It modulates the innate immune response of macrophages to LPS challenge, in part, by regulating the internalization and down-regulation of the TLR4 receptor complex. Human Fes tyrosine kinase interacts with tubulin and microtubules to stimulate microtubule assembly. c-Fes is a regulator of the tubulin cytoskeleton that may facilitate the Fes-induced morphological changes in myeloid hematopoietic and neuronal cells.

序列

Synthetic peptide located within the following region: ARDSAQAKRKYQEASKDKDRDKAKDKYVRSLWKLFAHHNRYVLGVRAAQL

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

产品性质

安全信息