Anti-FGFR1OP (AB2) antibody produced in rabbit

产品说明

一般描述

FGFR1 oncogene partner is a protein encoded by the FGFR1OP gene in humans. The fibroblast growth factor receptor 1 (FGFR1) oncogene partner called FOP is a centrosomal protein that is involved in the anchoring of microtubules (MTS) to subcellular structures.

免疫原

Synthetic peptide directed towards the middle region of human FGFR1OP

应用

Anti-FGFR1OP (AB1) antibody produced in rabbit is suitable for western blotting at a concentration of 1 μg/ml.

生化/生理作用

FGFR1OP (FGFR1 oncogene partner) also referred to as FOP encodes a hydrophilic centrosomal protein predominantly expressd in heart, liver, muscle, kidney, intestine, colon, adrenal gland, prostate, testis and pancreas. It interacts with EB1 and facilitates the microtubules anchoring to the centrosomes. It plays an important role in normal proliferation and differentiation of the erythroid lineage. Attenuation of Fgfr1 disrupts cochlear hair cell formation.

序列

Synthetic peptide located within the following region: LSDVHSPPKSPEGKTSAQTTPSKIPRYKGQGKKKTSGQKAGDKKANDEAN

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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