产品说明
一般描述
FOXD4 codes for a forkhead/winged helix-box transcription factor that enables the formation and maintenance of neural ectoderm in embryos. FOXD4 mutation has been linked to dilated cardiomyopathy, obsessive-compulsive disorder, and suicidality.
Rabbit anti-FOXD4 antibody recognizes human FOXD4.
免疫原
Synthetic peptide directed towards the C terminal region of human FOXD4
应用
Rabbit anti-FOXD4 antibody is suitable for western blot applications at a concentration of 1μg/ml
生化/生理作用
FOXD4 contains 1 fork-head DNA-binding domain. The W148R mutation in the forkhead domain of FOXD4, possibly resultsin reduced DNA binding capacity and altered transcriptional activity.
序列
Synthetic peptide located within the following region: ASALLRYQAVAEGSGLTSLAAPLGGEGTSPVFLVSPTPSSLAESAGPS
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 47 kDa |
| species reactivity | human |
| 浓度 | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| NCBI登记号 | NP_997188 |
| UniProt登记号 | Q12950 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... FOXD4(2298) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
