产品说明
一般描述
FOXK1 codes for the forkhead box K1 protein that is expressed in mouse neuroretinal cells. It modulates the transcriptional functions of Foxo4 and Mef2, and enhances cell proliferation and inhibits myogenic differentiation. Studies have reported that Fhl2-Foxk1 cascade modulates progenitor functions in skeletal muscle cells.
Rabbit Anti-FOXK1 antibody recognizes human, mouse, rat, chicken, and zebrafish FOXK1.
免疫原
Synthetic peptide directed towards the middle region of human FOXK1
应用
Rabbit Anti-FOXK1 antibody is suitable for western blot applications at a concentration of 0.25 μg/ml.
生化/生理作用
FOXK1 is a transcriptional regulator that binds to the upstream enhancer region (CCAC box) of myoglobin gene. It has a role in myogenic differentiation and in remodeling processes of adult muscles that occur in response to physiological stimuli.
序列
Synthetic peptide located within the following region: TSDLQLAAEFAAKAASEQQADTSGGDSPKDESKPPFSYAQLIVQAISSAQ
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 75 kDa |
| species reactivity | human |
| 浓度 | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| NCBI登记号 | NP_001032242 |
| UniProt登记号 | P85037 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... FOXK1(221937) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
