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Anti-GAD1, (N-terminal) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB2105927
规格纯度
affinity isolated antibody
参考价格
6305.78 *本价格含增值税费
促销
服务
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  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-GAD1, (N-terminal) antibody produced in rabbit
Anti-SCP
Anti-GAD
Anti-FLJ45882
产品介绍:

产品说明

免疫原

Synthetic peptide directed towards the N terminal region of human GAD1

生化/生理作用

This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form.

序列

Synthetic peptide located within the following region: MASSTPSSSATSSNAGADPNTTNLRPTTYDTWCGVAHGCTRKLGLKICGF

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRESNA.41

产品性质

生物来源rabbit
质量水平100
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量 67 kDa
species reactivityrabbit, guinea pig, bovine, dog, rat, human
浓度0.5 mg - 1 mg/mL
technique(s)western blot: suitable
NCBI登记号NM_000817
UniProt登记号Q99259
运输wet ice
储存温度−20℃
Gene Informationhuman ... GAD1(2571)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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