产品说明
一般描述
Guanosine monophosphate reductase 2 (GMPR2) is known to promote monocytic differentiation in HL-60 leukemia cells. Lack of GMPR2 expression has been linked to basal phenotype and patient outcome in breast carcinomas.
Rabbit Anti-GMPR2 antibody recognizes canine, bovine, human, mouse, rat, and zebrafish GMPR2.
免疫原
Synthetic peptide directed towards the C terminal region of human GMPR2
应用
Rabbit Anti-GMPR2 antibody is suitable for western blot applications at a concentration of 5 μg/ml.
生化/生理作用
GMPR2 catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. It plays a role in modulating cellular differentiation.
序列
Synthetic peptide located within the following region: GAGADFVMLGGMLAGHSESGGELIERDGKKYKLFYGMSSEMAMKKYAGGV
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 20 kDa |
| species reactivity | human, horse, rabbit, mouse, dog |
| 浓度 | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| NCBI登记号 | NP_001002002 |
| UniProt登记号 | Q9P2T1 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... GMPR2(51292) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
