产品说明
一般描述
Guanine nucleotide binding protein (G protein), β polypeptide 2-like 1 (GNB2L1) is a stably expressed housekeeping gene expressed in alveolar macrophage and neutrophils. The gene is hypothesized to encode a protein RACK1 (Receptor for activated C kinase 1). It is mapped on the telomeric position of chromosome 5q35.3.
免疫原
The immunogen for anti-GNB2L1 antibody: synthetic peptide derected towards the N terminal of human GNB2L1
应用
Anti-GNB2L1 antibody produced in rabbit is suitable for indirect ELISA and western blot applications.
生化/生理作用
Guanine nucleotide binding protein (G protein), β polypeptide 2-like 1 (GNB2L1) is a scaffold protein highly involved in the binding and anchorage of protein kinase C. It has been hypothesized that GNB2L1 may act as a regulatory cofactor of multidrug resistance protein 3 (MDR3/ABCB4) and is vital for the plasma membrane localization and for mediating translocation function of ABCB4.
序列
Synthetic peptide located within the following region: RLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGV
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 100 |
偶联物 | unconjugated |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
形式 | buffered aqueous solution |
分子量 | 35 kDa |
species reactivity | guinea pig, sheep, dog, rabbit, mouse, human, bovine, rat |
浓度 | 0.5 mg - 1 mg/mL |
technique(s) | western blot: suitable |
NCBI登记号 | NM_008143 |
运输 | wet ice |
储存温度 | −20℃ |
Gene Information | human ... RACK1(10399) mouse ... Gnb2l1(14694) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich