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Anti-HMOF/MYST1 (C-term) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB1300521
规格纯度
saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution
参考价格
4618.16 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-HMOF/MYST1 (C-term) antibody produced in rabbit
Anti-MYST1
Anti-Probable histone acetyltransferase MYST1
Anti-HMOF
Anti-MYST protein 1
Anti-MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1
产品介绍:

产品说明

一般描述

The MYST family of histone acetyltransferases, which includes MYST1, is named for the founding members MOZ (MYST3; MIM 601408), yeast YBF2 and SAS2, and TIP60 (HTATIP; MIM 601409). All members of this family contain a MYST region of about 240 amino acids with a canonical acetyl-CoA-binding site and a C2HC-type zinc finger motif. Most MYST proteins also have a chromodomain involved in protein-protein interactions and targeting transcriptional regulators to chromatin (Neal et al., 2000 [PubMed 10786633]).[supplied by OMIM].
MYST histone acetyltransferase 1 (MYST1), also known as human males absent on the first (HMOF), is encoded by the gene mapped to human chromosome 16p11.2. The encoded protein belongs to MYST family of histone acetyltransferases (HATs). MYST1 contains N-terminal chromodomain, involved in binding noncoding RNA and a central MYST histone acetyltransferase domain.

免疫原

HMOF/MYST1 (NP_115564, 414-449)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide at the C-term of human HMOF/MYST1.

生化/生理作用

MYST histone acetyltransferase 1 (MYST1) catalyzes the acetylation of Lys16 residue in histone H4. It also plays a vital role in various cellular processes, such as gene transcription, cell proliferation, differentiation and DNA repair response. MYST1 is essential for maintaining normal chromatin architecture of all cells of early male and female embryos.Aberrations in the gene expression leads to certain type of primary cancers.

外形

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRESNA.41

产品性质

生物来源rabbit
质量水平200
偶联物unconjugated
抗体形式saturated ammonium sulfate (SAS) precipitated
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
species reactivityhuman
technique(s)immunohistochemistry: 1:50-1:100
indirect ELISA: 1:1000
western blot: 1:100-1:500
NCBI登记号NP_115564
UniProt登记号Q9H7Z6
运输dry ice
储存温度−20℃
Gene Informationhuman ... MYST1(84148)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKnwg
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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