产品说明
一般描述
HOXB7 is a homebox protein that activates basic fibroblast growth factor (bFGF) in melanomas. It can also up-regulate various proangiogenic stimuli.
Rabbit Anti-HOXB7 (AB2) antibody recognizes bovine, human, mouse, and rat HOXB7.
免疫原
Synthetic peptide directed towards the C terminal region of human HOXB7
应用
Rabbit Anti-HOXB7 (AB2) antibody can be used for western blot applications at a concentration of 1.25 μg/ml.
生化/生理作用
HOXB7 belongs to the homeobox family. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXBThis gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of melanoma and ovarian carcinoma.
序列
Synthetic peptide located within the following region: IEIAHTLCLTERQIKIWFQNRRMKWKKENKTAGPGTTGQDRAEAEEEEEE
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 24 kDa |
| species reactivity | bovine, human |
| 浓度 | 0.5 mg - 1 mg/mL |
| technique(s) | immunofluorescence: suitable western blot: suitable |
| NCBI登记号 | NP_004493 |
| UniProt登记号 | P09629 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... HOXB7(3217) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
