产品说明
一般描述
HSPB1 is a small, ubiquitous heat shock protein that is involved in regulating cellular apoptosis. Studies have reported that downregulation of HSPB1 (Hsp27) in breast cancer cells can cause the upregulation of PTEN.
Rabbit Anti-HSPB1 (AB2) antibody binds to human HSPB1.
免疫原
Synthetic peptide directed towards the C terminal region of human HSPB1
应用
Rabbit Anti-HSPB1 (AB2) antibody can be used for western blot (1.25μg/ml) and immunohistochemistry (4-8μg/ml, using paraffin-embedded tissues) assays.
生化/生理作用
HSPB1, like the other heat shock proteins, is part of a complex system of molecular chaperones in epidermal keratinocytes.
序列
Synthetic peptide located within the following region: SLSPEGTLTVEAPMPKLATQSNEITIPVTFESRAQLGGPEAAKSDETAAK
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 23 kDa |
| species reactivity | human |
| 浓度 | 0.5 mg - 1 mg/mL |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| NCBI登记号 | NP_001531 |
| UniProt登记号 | P04792 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... HSPB1(3315) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
