产品说明
一般描述
IKAP (IKK-complex-associated protein) is considered as a subunit of the RNA Pol II elongator complex. It is also known as IKBKAP (Ikappakinase complex-associated protein or human elongator factor 1) and ELP1 (elongator protein-1). It has 37 exons and codes for 1332 amino acid IKAP protein, that is of ~150KD. It is present in most of the tissues. It is mapped to chromosome 9q31.
免疫原
a 16 amino acid peptide from near the carboxy-terminus of human IKAP.
生化/生理作用
Mutations in IKAP cause familial dysautonomia. It helps to conserve the proliferation of neural precursor and blocks its unexpected differentiation into neurons. It plays an important role in cell motility and migration.
联系
The action of this antibody can be blocked using blocking peptide SBP2337.
外形
Solution in phosphate buffered saline containing 0.02% sodium azide
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| MDL编号 | MFCD04118553 |
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | predicted mol wt 134-147 kDa |
| species reactivity | human, mouse |
| technique(s) | immunocytochemistry: suitable immunofluorescence: suitable indirect ELISA: suitable western blot: suitable |
| UniProt登记号 | O95163 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | human ... IKBKAP(8518) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
