产品说明
一般描述
KCNK10 (TREK2) codes for a potassium channel protein that is activated by 2-aminoethoxydiphenyl borate (2-APB). TREK2 is known to be expressed in normal and cancerous ovarian cells.
Rabbit Anti-KCNK10 antibody recognizes rabbit, canine, human, mouse, and rat KCNK10.
免疫原
Synthetic peptide directed towards the C terminal region of human KCNK10
应用
Rabbit Anti-KCNK10 antibody is suitable for western blot applications at a concentration of 2.5 μg/ml.
生化/生理作用
KCNK10 is one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The message for this gene is highly expressed in the kidney and pancreas. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations. The protein is stimulated strongly by arachidonic acid and to a lesser degree by membrane stretching, intracellular acidification, and general anaesthetics. Three transcript variants have been identified for this gene.
序列
Synthetic peptide located within the following region: EDVQKIYKTFRNYSLDEEKKEEETEKMCNSDNSSTAMLTDCIQQHAELEN
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 59 kDa |
| species reactivity | mouse, guinea pig, horse, dog, rabbit, rat, human |
| 浓度 | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| NCBI登记号 | NP_066984 |
| UniProt登记号 | P57789 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... KCNK10(54207) |
安全信息
| 储存分类代码 | 10 - Combustible liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
