产品说明
一般描述
KLF8 functions as a downstream target of focal adhesion kinase (FAK) during cell cycle progression and cyclin D1 regulation. It has also been implicated in oncogenic transformation. Furthermore, KLF8 is known to have prognostic implications in gastric adenocarcinomas.
Rabbit Anti-KLF8 (AB2) antibody recognizes human, mouse, and rat KLF8.
免疫原
Synthetic peptide directed towards the middle region of human KLF8
应用
Rabbit Anti-KLF8 (AB2) antibody can be used for western blot applications at a concentration of 0.5μg/ml. It has also been used for immunohistochemistry applications.
生化/生理作用
KLF8 is abnormally expressed in female patients with X autosome translocation t(X;21)(p11.2;q22.3) and non-syndromic mental retardation.
序列
Synthetic peptide located within the following region: LEIPSDSEESTIESGSSALQSLQGLQQEPAAMAQMQGGESLDLKRRRIHQ
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 39 kDa |
| species reactivity | human, dog |
| 浓度 | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| NCBI登记号 | NP_009181 |
| UniProt登记号 | O95600 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... KLF8(11279) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
