Anti-KLHL5 antibody produced in rabbit

产品说明

一般描述

KLHL5 is a kelch-like protein that has a BTB domain. It is expressed abundantly in thyroid, ovary and adrenal gland, and to a lesser extent in spinal cord, lymph node, prostate, testis and trachea.
Rabbit Anti-KLHL5 antibody recognizes canine, mouse, rat, and human KLHL5.

免疫原

Synthetic peptide directed towards the N terminal region of human KLHL5

应用

Rabbit Anti-KLHL5 antibody is suitable for western blot applications at a concentration of 5 μg/ml.

生化/生理作用

The kelch-repeat protein family is a recently found new kind of actin-binding protein. It is characterized by tandemly arranged motifs of about 50 amino acids. Most members of the kelch-repeat family were cytoskeletal proteins implicated in various cellular processes, such as actin cytoskeleton interaction, cytoplasmic sequestration of transcription factors and cell morphology. During the large-scale sequencing analysis of a human fetal brain cDNA library we found a novel kelch-like protein gene 5, KLHL5, KLHL5 has high identity with Drosophila kelch protein and many other family members. A novel splicing variants of KLHL5, named KLHL5b and the expression pattern of KLHL5b in many tissues.

序列

Synthetic peptide located within the following region: NRGQTGANGGRKFLDPCSLQLPLASIGYRRSSQLDFQNSPSWPMASTSEV

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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