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Anti-KLHL7 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB2104176
规格纯度
affinity isolated antibody
参考价格
6305.78 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-KLHL7 antibody produced in rabbit
Anti-SBBI26
Anti-KLHL6
产品介绍:

产品说明

一般描述

Kelch like family member 7 (KLHL7) has BTB (bric-a-brac, tram track, and broad complex) domain in its N-terminal, BACK (BTB and C-terminal Kelch) domain and kelch domain. In human chromosome, the gene KLHL7 is localized on 7p15.3.

免疫原

Synthetic peptide directed towards the middle region of human KLHL7

生化/生理作用

KLHL7 mediates ubiquitin-proteasome protein-degradation pathway by ubiquitinating cullin (E3) ligase complexes. Mutations in KLHL7 leads to autosomal dominant retinitis pigmentosa, leading to loss of rods and cones photoreceptors. Mutations in KLHL7 also leads to autosomal recessive crisponi syndrome (CS)/cold-induced sweating syndrome type 1 (CISS1), with high lethality in neonates. KLHL7 is associated with various cancers and Sjogren′s syndrome, an autoimmune disorder.

序列

Synthetic peptide located within the following region: AVGSIVYVLAGFQGVGRLGHILEYNTETDKWVANSKVRAFPVTSCLICVV

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

产品性质

生物来源rabbit
质量水平100
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量 62 kDa
species reactivityrat, rabbit, horse, human, guinea pig, mouse, dog
浓度0.5 mg - 1 mg/mL
technique(s)western blot: suitable
NCBI登记号NM_018846
UniProt登记号Q8IXQ5
运输wet ice
储存温度−20℃
Gene Informationhuman ... KLHL7(55975)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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