产品说明
一般描述
L(3)mbt-like 2 (L3MBTL2) is known to associate with histone deacetylase 3 (HDAC3). HDAC3 and L3MBTL2 are involved in histone deacetylation and transcriptional repression.
Rabbit Anti-L3MBTL2 (AB1) antibody recognizes canine, bovine, rat, and human L3MBTL2.
免疫原
Synthetic peptide directed towards the C terminal region of human L3MBTL2
应用
Rabbit Anti-L3MBTL2 (AB1) antibody can be used for western blot (0.625μg/ml) and immunohistochemical (4-8μg/ml, using paraffin-embedded tissues) assays.
生化/生理作用
L3MBTL2 contains 1 FCS-type zinc finger and 4 MBT repeats. It is putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis.
序列
Synthetic peptide located within the following region: EYDQWVDCESPDIYPVGWCELTGYQLQPPVAAEPATPLKAKEATKKKKKQ
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 79 kDa |
| species reactivity | guinea pig, bovine, human, horse, dog, rabbit |
| 浓度 | 0.5 mg - 1 mg/mL |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| NCBI登记号 | NP_113676 |
| UniProt登记号 | Q969R5 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... L3MBTL2(83746) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
