Anti-LMAN1 antibody produced in rabbit

产品说明

免疫原

Synthetic peptide directed towards the middle region of human LMAN1

应用

Anti-LMAN1 antibody produced in rabbit is suitable for western blotting at a concentration of 1.25μg/ml.

生化/生理作用

LMAN1 (lectin, mannose-binding, 1) gene encodes a type I integral membrane protein localized in golgi apparatus and endoplasmic reticulum membrane. It is a mannose specific lectin that may facilitate the sorting or recycling of proteins, lipids, or both. It could be used for recognizing sugar residues in glycoproteins, glycolipids, or glycosylphosphatidyl inositol anchors. LMAN1 forms a complex with MCFD2 and assists in forming a specific cargo receptor for the ER-to-Golgi transport of selected proteins. Mutation in LMAN1 gene results in autosomal recessive bleeding disorder characterized by combined deficiency of factor V and factor VIII. Hence, it leads to collective decline of both clotting proteins.

序列

Synthetic peptide located within the following region: DKKKEEFQKGHPDLQGQPAEEIFESVGDRELRQVFEGQNRIHLEIKQLNR

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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