Anti-MINA (AB2) antibody produced in rabbit

产品说明

一般描述

MyC induced nuclear antigen (MINA, MINA53) is a direct gene target of myc which is believed to be involved in mammalian cell proliferation. MINA53 is prominently expressed in tumor cells and proliferating, undifferentiated spermatogona. MINA53 activity extends from the spermatogonial stage up to meiotic prophase in spermatogenesis.

特异性

Anti-MINA (AB2) polyclonal antibody reacts with chicken, human, mouse, rat, canine, and bovine myC induced nuclear antigen proteins.

免疫原

Synthetic peptide directed towards the C terminal region of human MINA

应用

Anti-MINA (AB2) polyclonal antibody is used to tag myC induced nuclear antigen for detection and quantitation by Western blotting and in plasma by immunohistochemical (IHC) techniques. It is used as a probe to determine the roles of myC induced nuclear antigen in cell proliferation.

生化/生理作用

MINA protein is directly involved in ribosome biogenesis, most likely during the assembly process of preribosomal particles. MINA is also involved in cell proliferation. MINA may have a role in esophageal squamous cell carcinoma, colon cancer and lung cancer

序列

Synthetic peptide located within the following region: HGLRFPLSHLDALKQIWNSPAISVKDLKLTTDEEKESLVLSLWTECLIQV

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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