产品说明
一般描述
Neurogenic differentiation 2 (NEUROD2), a member of the neuroD family of neurogenic basic helix-loop-helix (bHLH) proteins, is an E-box binding transcription factor that can induce transcription from neuron-specific promoters. NEUROD2 which helps determine neuronal cell fates induces neurogenic differentiation in non-neuronal cells.
Rabbit polyclonal anti-NEUROD2 antibody reacts with bovine, canine, human, mouse, and rat neurogenic differentiation 2 transcription factors.
免疫原
Synthetic peptide directed towards the N terminal region of human NEUROD2
应用
Rabbit Anti-NEUROD2 (AB2) antibody can be used for western blotting assays at a concentration of 0.5μg/ml. The antibody has been used for immunohistochemistry assays.
Rabbit polyclonal anti-NEUROD2 antibody is used to tag neurogenic differentiation 2 for detection and quantitation by immunocytochemical and immunohistochemical (IHC) techniques. It is used as a probe to determine the presence and roles of neurogenic differentiation 2 in neuronal cell determination and differentiation.
生化/生理作用
NEUROD2 is a member of the neuroD family of neurogenic basic helix-loop-helix (bHLH) proteins. Expression of NEUROD2 can induce transcription from neuron-specific promoters, such as the GAP-43 promoter, which contain a specific DNA sequence known as an E-box. NEUROD2 can induce neurogenic differentiation in non-neuronal cells in Xenopus embryos, and is thought to play a role in the determination and maintenance of neuronal cell fates.This gene encodes a member of the neuroD family of neurogenic basic helix-loop-helix (bHLH) proteins. Expression of this gene can induce transcription from neuron-specific promoters, such as the GAP-43 promoter, which contain a specific DNA sequence known as an E-box. The product of the human gene can induce neurogenic differentiation in non-neuronal cells in Xenopus embryos, and is thought to play a role in the determination and maintenance of neuronal cell fates.This gene encodes a member of the neuroD family of neurogenic basic helix-loop-helix (bHLH) proteins. Expression of this gene can induce transcription from neuron-specific promoters, such as the GAP-43 promoter, which contain a specific DNA sequence known as an E-box. The product of the human gene can induce neurogenic differentiation in non-neuronal cells in Xenopus embryos, and is thought to play a role in the determination and maintenance of neuronal cell fates.
序列
Synthetic peptide located within the following region: AEVKEEGELGGEEEEEEEEEEGLDEAEGERPKKRGPKKRKMTKARLERSK
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 41 kDa |
| species reactivity | dog, rat, human, bovine, horse, mouse |
| 浓度 | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| NCBI登记号 | NP_006151 |
| UniProt登记号 | Q15784 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... NEUROD2(4761) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
