您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 品牌 > Sigma-Aldrich > Anti-Parkin antibody produced in rabbit

Anti-Parkin antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB4502077
规格纯度
affinity isolated antibody
参考价格
5874.82 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-Parkin antibody produced in rabbit
Parkinson disease protein 2
PARK2
Parkinson juvenile disease protein 2
PRKN
PRKN2
产品介绍:

产品说明

一般描述

Anti-Parkin Antibody detects endogenous levels of total Parkin protein.
Parkin RBR E3 ubiquitin protein ligase (PARK2) is a putative tumor suppressor gene. It possesses an amino-terminal region containing the Ubl (ubiquitin like) domain and a carboxy-terminal region with four zinc coordinating domains. Parkin is a 465 amino acid protein, which is part of the ubiquitin-proteasome system that targets proteins for degradation. The gene encoding it is localized on human chromosome 6q25.2-q27.

免疫原

The antiserum was produced against synthesized peptide derived from human Parkin.

Immunogen Range: 1-50

应用

Anti-Parkin antibody produced in rabbit has been used in western blotting.

生化/生理作用

The expression of parkin RBR E3 ubiquitin protein ligase (PARK2) has been found to be altered in various malignancies. Parkin has a neuroprotective E3 ligase activity and polyubiquitylates proteins before degradation. Mutations in the gene encoding it have been linked to autosomal recessive juvenile parkinson (ARJP) disease.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号MFCD03702182

产品性质

生物来源rabbit
质量水平100
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量antigen 51 kDa
species reactivityrat, human, mouse
浓度~1 mg/mL
technique(s)ELISA: 1:5000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI登记号O60260
运输wet ice
储存温度−20℃
Gene Informationhuman ... PARK2(5071)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKnwg
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

推荐产品